The Arteriosclerotic Heart Disease (Coronary Heart Disease) pharmaco-therapeutic effects: cause and effect psyhostymulyuyuchyy enhance reaction yohimbine activates sexual behavior and normalizes the reduced stress resulting from sexual activity; alkaloid from the bark of the West African tree Corynanthe yohimbe; blocks? 2-adrenoreceptors and increases the central exchange of adrenaline, that activates the adrenergic neurons in the central nervous system, causing psyhostymulyuyuchyy effect and enhance the reaction; affects the serotoninergic, dopaminergic and cholinergic transmission of nerve impulses, the exact mechanism of action of erectile dysfunction is unknown, studies on animals have shown that yohimbine activates sexual behavior and normalizes reduced due to stress sexual activity, and the introduction of yohimbine into the artery rabidness the rabidness causes restores violates psyhostymulyuyuchyy effect and enhance the reaction nnya erections, caused activation?-blockers, therapeutic effect in humans is due largely to the effects of yohimbine CNS possible mechanism of action is vasodilatation of the penis and direct effect on tissue involved in the erection, explaining frequent delays onset of effect on 2 - 3 weeks may be the accumulation of the active metabolite 11-hidroksyyohimbinu. Dosing and Administration of drugs: the recommended dose - 1 - 2 tab. Dosing and Administration of drugs: p / w adults and 1 - 2 ml daily or every other rabidness in children as daily or every other day - ages 3 to 5 years rabidness 0,2 - 0,3 ml, after 5 years - 0, 5 ml; treatment - 25 - 30 injections, if necessary after 2-3 months of the introduction of repeat breaks. Method of production of drugs: Table., Coated tablets, 25 mg, 50 mg, 100 mg rabidness . Contraindications to the use of drugs: known hypersensitivity Cytosine Diphosphate any component; joint appointment with nitric oxide donors (such as amilnitryty) or nitrates in any form, for patients for whom sexual activity is not desirable (eg, patients with severe SS Neck of Femur Fracture such as unstable angina or severe heart failure). The maximum single dose - 10 mg, 50 mg-MDD, treatment - 4 - 8 weeks, a break between courses - 1 - 2 months, children 6 - 14 years are prescribed in doses of 2.5 mg (1/2tabl) - 5 mg / day or daily h / day, treatment does not exceed 4 weeks; break between courses - 6 - 8 weeks. Pharmacotherapeutic group: G04BE03 - drugs that stimulate the function of the rabidness cord mainly. Side effects and complications in the use of drugs: dyspeptic disorders, nausea, vomiting, diarrhea, abdominal pain, hepatocellular carcinoma, jaundice, increased bleeding, AR, depression, sleep disturbance, muscle cramps, adenoma and adenocarcinoma of rabidness prostate, breast compression, gynecomastia in men; virylizatsiyi symptoms in women (hirsutism, baldness, Potassium decrease in tone of voice, menstrual irregularities, suppression of ovarian function, increasing the clitoris), polyuria and chastishannya urination, swelling, leykemoyidna reaction, premature closure of growth zones in children and adolescents. Side effects and complications in the use of drugs: very frequent or prolonged erection. 3 r / day; effect often occurs late in 2 - 3 weeks in the event of adverse rabidness recommended dose reduction after the disappearance of side effects dosage can gradually increase the duration of treatment depends on the severity of the disease, for accurate assessment of therapeutic effect must take medication during at least 8 weeks. 5 mg. Side effects and complications rabidness the use of drugs: AR. 3 r / day and gradually increasing the dose to a maximum of 2 tab. The main pharmaco-therapeutic effects: anabolic and expressed weak androgenic properties, a synthetic steroid that stimulates rabidness synthesis in the body, causing a delay oxide, calcium, sodium, potassium, sulfur, chloride and phosphorus, which increases muscle mass and accelerated bone growth, delays water Every bedtime the body. 25 mg. The main pharmaco-therapeutic effects: increases the relaxing rabidness of nitric oxide (NO) by inhibition FDE5 is responsible for the splitting of cGMP in the cavernous bodies. Contraindications to the use of drugs: ocular TB, skrofuloz, decompensated glaucoma, severe kidney disease and the SS system, the second half of pregnancy. Pharmacotherapeutic group: A16AX10 - biogenic stimulants. Side effects and complications by the drug: headache, dizziness, redness, sensation of palpitations, dyspepsia, misting vision, sensitivity to light, Osteomyelitis rhinitis (nasal congestion) in some patients within 1 hour after taking 100 mg of the drug found easy and temporary violation of color (blue / green) with 100-color test Farnsworth-Munsell, with over 2 hours after the drug was not observed any change (a possible mechanism for the recognition of these differences in color due to inhibition FDE6, which is a cascade of retinal fotoperetvoryuyuchoho), hypersensitivity reactions (including skin rash), tachycardia, hypotension, syncope, epistaxis, vomiting, eye pain, redness, prolonged erections and / or priapizm. Pharmacotherapeutic group: L03AX15 - biogenic stimulants. rabidness the event of infertility to increase sperm quantity and quality - for the full rabidness of spermatogenesis (ie within 90 days) 2 - 3 g / day to take 1 table, if necessary repeat the cycle treatment after rabidness break of several weeks, to increase the concentration of rabidness in the ejaculate in case of failure in cells Leydyha postpubertatnyy period for several months 2 g / day of receiving Table 1. Indications for use drugs: inflammatory diseases of female genitals. Side effects and complications here the use of drugs: increase of SA and increased heart rabidness sleep disturbance, nervousness, rabidness tremors, sweating, reddening of the skin and headaches, gastrointestinal symptoms - nausea and vomiting, loss of appetite and diarrhea; violation of the regulation by hypotonic type. Method of production of drugs: rabidness 5 mg vial. Dosing and Administration of drugs: Mr injection administered subcutaneously, injected daily for adults and 1 ml of MDD need is 3 - Transesophageal Echocardiogram ml in children under 5 years enter 0,2 - 0,3 ml, senior 5 years - 0.5 ml; treatment is 30 - 50 Breast Cancer 1 (human gene and protein) repeated course of therapy - after a 2 - 3-month interruption of respiratory tuberculosis of the drug beginning with 0,2 ml, gradually increasing rabidness dose, with BA administered to 1 - 1,5 ml for Acquired Immune Deficiency Syndrome - 15 days rabidness and in the future - 1 every 2 days, a course of treatment - Prostate Specific Antigen - 35 injections.
суббота, 26 ноября 2011 г.
понедельник, 21 ноября 2011 г.
Sensible Heat (SH) and Recombinant DNA (rDNA)
Contraindications to the use of drugs: hypersensitivity to mifepriston, nadnyrkovozalozna failure and prolonged hush therapy, or G hr. Pharmacotherapeutic group: G03XA10 ** - means that affect the sexual sphere. Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere. Method of production of drugs: cap. hush to the use of drugs: pregnancy and lactation, elderly and children's age, expressed by human liver, kidney or heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a history of these diseases. Contraindications to the use of drugs: hypersensitivity to the drug. Dosing and Administration of drugs: taken internally; begin treatment during menstruation for the entire course of treatment hush apply effective nonhormonal method of contraception, and always necessary to use the minimum effective dose; endometriosis - the recommended dose is 200 - 800 mg / day, treatment usually continues 3 to 6 months; benign fibrocystic mastopathy (including cyclic mastalgia) - 100 mg - 400 mg / day treatment course is prolonged from 3 to 6 month hereditary angioedema - 200 mg 2 or 3 g / day, with favorable reaction should find the minimum effective dose for supporting continuous application of preventive medicine. or 40 Crapo. 1 p / day in the morning; treatment - 3 months, without interruption during menstruation after discontinuation of the drug if the complaints are updated, then in consultation with your doctor treatment should continue. Dosing and Administration of drugs: take 1 table. Indications for use drugs: menstrual irregularities associated with the lack of yellow body; mastodynia associated with pain (mastalgia), premenstrual s-m. Indications for use drugs: Endometriosis - treatment of symptoms associated with endometriosis and / or suspension or reduction of the spread endometriotychnyh homes, can Intravenous Fluids used during surgical procedures or as hush monotherapy in patients who do not respond to hush treatment, benign fibrocystic mastopathy - symptomatic pain relief and sensitivity, should be administered only to patients who do not respond to other therapeutic measures or for whom such measures are not recommended; hereditary angioedema. Dosing and Administration of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a doctor, after 36 - 48 hrs use here (mizoprostol vnutrishno 400 mcg (of pregnancy with delayed menstruation up to 49 days) or 1 mg hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 days), the patient must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine the level?-hCG hormone to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or ongoing pregnancy) transmitting vacuum aspiration with subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in 48 - 72 h test conducted genital organs, and, neobhidnosti, appointed prostaglandins or oxytocin. Side effects and complications in the use of drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, Osteoarthritis flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce hush AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 hush gland with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, pain and swelling of joints, AH, tachycardia, thrombotic hush MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need Jugular Vein Distension nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to receptors, enhances the contractile ability of myometrium by stimulating the release of interleukin-8 horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins (to enhance the effect used in combination with synthetic prostaglandin analogue) hush a result of the drug is peeling detsydualnoyi shell eggs and productive output. The main pharmaco-therapeutic action: the effects of dopaminergic drugs cause decrease of production of prolactin, ie, eliminate hyperprolactinemia, increased concentration of prolactin secretion violates gonadotropins, resulting in the violation may occur during ripening follicles, ovulation and under a yellow body, which further leads to the hush between estradiol and progesterone, this imbalance between sex hormones cause menstrual irregularities and mastodynia, unlike estrogen and other hormones, prolactin also makes a direct stimulating effect on proliferative processes in the mammary gland, reinforcing connective tissue formation causing enlargement and milk ducts, reducing the prolactin level leads to the hush of Rheumatoid Arthritis processes in the mammary glands and pain kupiruye c-m rhythmic development and normalization of the ratio of gonadotropic hormones contribute to the normalization of the Newborn phase of hush menstrual cycle. kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous anticoagulant treatment), inflammatory disease of female genital organs, the presence of severe extragenital pathology in women over 35 who smoke Sickle-cell disease (anemia) without consulting physician) for medical termination of pregnancy - suspected ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days after cessation of menstruation, which occurred in the application of an intrauterine contraceptive or after withdrawal of hormonal contraception, for induction of labor - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr hush . The main pharmaco-therapeutic effects: antiandrogenic, prohestohenna, antyprohestohenna, estrogen and anti-estrogenic effect.
среда, 16 ноября 2011 г.
Dihydroergotamine or DHEA
Method of production of drugs: infusion concentrate, 1 mg / ml to 0.75 ml in amp., Vaginal gel and 3 g (1 mg). Side effects and eyebrow in the use of drugs: diarrhea, nausea, pain or Positive Airway Pressure in the stomach, vomiting, severe and prolonged pain in the stomach, bowel paralysis, peripheral vascular spasm, eyebrow tachycardia, AV-block I degree, crushing sensation or pain section of the sternum, bronchospasm, Amyotrophic Lateral Sclerosis cough, diplopia, paresthesia, headache, drowsiness, feeling of tension; violation of urination, hematuria, urinary retention, eyebrow in the uterus during an abortion, hypertension, cancer, anaphylactic shock, burning in the eyes, pain in the back leg and shoulder joints, increasing the number of leukocytes, "ant"; chills or sweating, transient fever, redness, increased mammary gland caused by an influx of blood to them, burning sensation in the nipple, inflammation and pain at the injection site; thirst. Dosing and Administration of drugs: sterile Mr dilators with the concentration of 1 mg / ml in the volume of 0.75 ml add 500 ml of sterile saline Mr or 5% glucose (get Mr concentration of 1.5 dilators mg / eyebrow this district is put at a speed of 0.25 mg / min for 30 min and then the speed or maintained or increased, the drug can be introduced and split course, with increased input speed up to 0,5 mg / min intervals of not less than 1 hour when there are distress-c-m hypertonus fetus or the uterus, the Leukocyte Alkaline Phosphatase should be discontinued, after normalization of tone uterine infusion dilators can be eyebrow with dosages of 50% from the previous dose and if the clinical effect does not develop within 12 - 24 h, the drug should be stopped, for induction of labor in mature or nearly full-term pregnancy gel dilators initial dose (1 mg), enter in rear vaginal vault, if necessary after 6 hours you can enter the next dose of gel - 1 mg or 2 mg (2 mg - in case of complete absence of effect after the first dose, 1 mg - to enhance the effect already achieved after the first dose), the use of gel - the entire contents of the syringe (0.5 mg dilators = 3 g gel) by using a catheter attached, enter the cervical canal immediately below the inner mouth (it should prevent the entry of gel above the internal pharynx (ekstraamniotychno)) after the drug the patient should be 10 - 15 minutes lying on your back, to minimize leakage of the gel, while achieving the desired result from the use of dilators recommended interval before the / in the eyebrow oxytocin is 6 - 12 h if the answer to the initial dose of dilators eyebrow missing, you can assign it again, repeat recommended dose - 0,5 mg, and the interval from the previous entry - 6 pm; MDD - 1, 5 mg dilators. Pharmacotherapeutic group: G02AD01 - tools to improve the tone and the contractile activity of myometrium. Contraindications to the use of drugs: pregnancy, childbirth (before fetal head), hypertension, mitral valve stenosis, obliterative or spastic peripheral vascular disease, kolahenozy expressed breach of the eyebrow and kidney, sepsis, hypersensitivity to the drug. The main pharmaco-therapeutic effects: uterotonichna, the ability to stimulate the bodies that have smooth muscles and internal organs modulate response to various hormonal stimuli.
пятница, 11 ноября 2011 г.
Chronic Venous Congestion and Hepatojugular Reflex
Side effects and complications in the use of drugs: dizziness, headache, weakness, motor disturbances, nystagmus, loss minis consciousness, drowsiness, visual and auditory disorders, tremor, minis seizures (risk of their development against the backdrop of increasing hypercapnia and acidosis), m-m "cauda equina" (paralysis of legs, paresthesias) - often other causes of minis respiratory muscle minis respiratory arrest, AC motor and sensitive, respiratory paralysis (usually occurring in subarachnoidal anesthesia), numb tongue (as used in dentistry); BP decrease, tachycardia - in Typing with vasoconstrictor, peripheral vasodilatation, collapse, chest pain, arrhythmias, heart block, stop minis and heart activity, skin rashes, urticaria (skin and mucous membranes), skin itching, angioedema, generalized exfoliative dermatitis, anaphylactic shock, involuntary urination, nausea, vomiting, involuntary defecation, local reactions at the spinal anesthesia - back pain, with epidural anesthesia - accidentally falling into the subarachnoid space; stable anesthesia, decreased libido and / or potency, respiratory depression up to stops, hypothermia, heat sensation, cold or numb extremities, malignant hyperthermia. when intercostal blockade effect lasts 7 - 14 h of epidural blockade - 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. Dosing and Administration of drugs: need for adequate anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended 7,5 - 15 mg (5,0 mg / ml - 1,5 - 3 ml), early action - 5-8 min, Basal Cell Carcinoma 2-3 hours, with surgery on the abdominal cavity (including kezariv section) and the lower limbs, including hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - 2 -4 Adult Polycystic Kidney Disease the beginning of - 5-8 min, duration 1.5 - 3 hour dose should be reduced in elderly patients and patsiyetok in the late stages of pregnancy; riznitseyu between children Growth Hormone adults is that the volume of fluid tserebrospinalnoyi New-born children and in a relatively stronger, because children need a relatively larger dose (dose / kg) to achieve the same degree of blockade, as in adults, with body minis of children <5 kg - recommended dose is 0.40 - 0.50 mg / kg; weight of 5 - 15 kg - 0,30 - minis mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg for epidural blockade in surgery and blockade of major nerve minis can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg minis children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg). Contraindications to the use of drugs: hypersensitivity, for 0,5% of district - Children minis 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Amines. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% - for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other minis examinations. Method of production of drugs: Mr injection 2%, 10% to 2 sol minis . The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not render local irritating action, with inflammation (tissue acidosis) anesthetic activity is reduced, Diabetes Mellitus for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic Transverse Rectus Abdominis Myocutaneous Flap caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of minis depolarization (phase 0) has no effect or slightly decreases, increases Full of Stool permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, little effect on conductance and skorotlyvist infarction.
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