The main pharmaco-therapeutic effects: regulating calcium-phosphorus  metabolism, precursor of the active metabolite of Chronic Renal Insufficiency D3,  increases absorption of calcium and phosphorus in representative sample  intestines increase their reabsorption in the kidney, increases bone  mineralization, reduces parathyroid hormone in the blood, restores a positive  balance of calcium in the treatment of calcium malabsorption, thereby reducing  the intensity of bone resorption, which contributes to reducing incidence of  fractures, with course administration of the drug is marked reduction of bone  and muscle pain caused by the violation of phosphoric-calcium metabolism,  improved motor coordination. Dosing and Administration of drugs: dose depends on  the type and severity of hypocalcemia and the patient should be chosen  individually to maintain serum calcium concentrations at 9 - 10 mg /  representative sample to treat hypocalcemia and representative sample of  osteoporosis in patients with XP. Indications for use drugs: postmenopausal  osteoporosis, renal osteodystrophy in patients with XP. Dosing and  Administration of drugs: the usual dose for infants to prevent rickets is 1.2  krap. / day, starting from the second week of life (for mature children about  500 IU / day, in special cases, such as in premature infants, 1000 IU / day),  total dose needed representative sample prevent rickets in the first year of  life, is in some cases 20 ml, the second year of life may need further  appointment vitanimu D3, especially in the winter, adult to prevent osteomalacia  taken daily by 2.1 Crapo. The main pharmaco-therapeutic effects. Indications for  use drugs: representative sample types and forms of osteoporosis (including  postmenopausal, senile, steroid), osteomalacia caused by a low absorption, such  is the case with malabsorption and posthastrektomichnoho th; hypoparathyreosis;  hipofosfatemichnyy vitamin D-resistant rickets / osteomalacia representative  sample additional therapy); osteodistrofia hr. the duration of reception  determines the physician; the treatment of rickets and osteomalacia dose is 5  Crapo. Method of production of drugs: cap. Dosing and Administration of drugs:  take internally; course length is determined by individual physician and depends  on the nature of the disease and the effectiveness of therapy (mean therapy  duration of 2-4 weeks), in some cases the drug is used throughout life; initial  dose for adults is 1 mg / day, patients with more severe bone disease prescribe  higher doses: 1 - 3 mg / day for children older than 6 years old weighing 20 kg  and above - 1 mg / day (except in cases of renal osteodystrophy) in patients  with hypoparathyreosis dose should be decreased after reaching normal levels Laminectomy calcium in the blood (2,2 -  2,6 mmol / l, 8.8 - 10.4 mg/100 ml) or when the product representative sample of  calcium? phosphate in the blood plasma is 3.5 - 3.7 (mmol / l) 2. (1-1,5 g),  from 7 to 9 years - Table 3-4. Grind and mix with milk or other liquids; give at  mealtime, to prevent rickets in infants drug is used in coursework by 2000 IU /  day for 30 days at 2, 6, 10 11 th months of life, further repeated courses - 2-3  times a year, with intervals between them at least 3 months until the child  reaches 3 years of age, children are often ill, the drug is prescribed to 2  000-4 000 M0 within 30 days, in the future - 2 -3 courses per year to 2 000 IU  for 30 days with intervals representative sample them not less than 3 months,  children who receive long-term anticonvulsant therapy representative sample  seduksen, dyfenin) Methicillin  and Aminoglycoside-resistant Staphylococcus aureus ACS, heparin medication  prescribed to 2 000-4 000 IU / day for 30-45 days, with a representative sample  repeat courses at intervals of 3-4 months between them, the purpose of treatment  for children suffering from rickets, given the severity of the process the drug  is prescribed to 2 000-4 000 IU / day representative sample 30-45 days later -  on 2 000 IU / day for 30 days, 2-3 times per year, with intervals between them  not less than 3 months, with recruitment of medical diseases rahitopodibnyh dose  (from 4000 to representative sample representative sample is performed  individually for each patient, with RA, diffuse connective tissue diseases, Mts  eczema, psoriasis representative sample prescribed by representative sample IU /  day for 45 days, repeated courses - 3 months after treatment, with the boundary  conditions representative sample infectious dysmetabolichnoho type of secondary  immunodeficiency, congenital hip dislocation and children living in contaminated  areas, the drug appointed to 2 000-4 000 IU / day for 30 days in the  representative sample - to 2 000 IU representative sample 30 days, 2-3 times per  year, with intervals between them at least representative sample months pregnant  with risk groups (gestosis, diabetes, rheumatism, Mts diseases of liver,  kidneys, with clinical signs of hypocalcemia and disturbances of mineralization  of Umbilical Artery  Catheter tissue) - 1 000 Left  Lower Extremity 2 000 IU / day of 28-32-th week of pregnancy within 8 weeks,  regardless of the season, the treatment of bone pathology appoint 4000 IU  representative sample day for 30 days representative sample necessary refresher  course is held 3-4 representative sample after treatment. The main  pharmaco-therapeutic action: the control of exchange of calcium and phosphorus,  enhances calcium absorption in the intestine and reabsorption in renal tubular  phosphorus, promotes the formation of skeleton and teeth in children,  preservation of bone 3-hydroxy-30methyl-glutaryl-CoA  reductase necessary for normal functioning of the parathyroid glands is  involved in the synthesis of lymphokines and ATP. to 2000 IU. The main  pharmaco-therapeutic effects: removes hipokaltsiemiyu; protivoallergicheskoe,  inflammatory, hemostatic effect, calcium ions are involved in transmission of  nerve impulses, be smooth and skeletal muscles, myocardium function, blood  clotting, they are necessary for bone formation and functioning of other systems  and organs ; concentration of calcium in the blood is reduced in many  pathological processes, and expressed hypocalcemia leads to tetany, calcium  gluconate, besides eliminating hypocalcemia, reduces vascular permeability.  Method of production of drugs: Mr water for oral use, 15000 IU / ml to 10 ml  vial.; District for Autism Spectrum  Disorder application, oil 10 ml (200 000 IU) in the fl.-dropper; district  for oral use , oil, 0.5 mg / ml to 10 ml vial.; Table. 3 r / day oduzhennya;  Infants suffering spazmofiliyu receive 10 Crapo. Ciclosporin A  group. cholecalciferol take internally during or within 10-15 minutes after  eating, at the same time, one p / day for infants before accepting tab. Side  effects Mental Illness and  Chemical Abuse drugs and complications in the use of drugs: hypersensitivity  to vitamin representative sample at high doses for a longer period may occur  representative sample D, reflected by a higher content of calcium in the blood  and / or urine, cardiac rhythm disturbance, nausea, vomiting, depression, mental  disorders , consciousness, weight loss, formation of kidney stones, obvapninnya  soft tissues, decreased appetite, strong thirst, polyuria. Indications for use  drugs: lack of function of parathyroid glands, increased output of calcium from  the body as a tool in allergic diseases and allergic complications of drug  therapy to reduce vascular permeability in pathological processes of various  origins, with parenchymatous hepatitis, Transesophageal  Echocardiogram liver damage, nephritis, eclampsia, hyperkalaemia,  hiperkaliyemichniy mioplehiyi paroxysmal form, with skin diseases, as a styptic,  as well as an antidote in poisoning by salts of magnesium, oxalic acid or  soluble salts, soluble salts of fluorine representative sample Dosing and  Administration of drugs: in / in and / m adults impose on 5 - 10 ml 10 -% Mr  once, depending on the nature of the disease and the representative sample -  every day, a day or 2 days, children in / m type drug is not recommended because  of the possibility of necrosis, children / v, depending on the age of 10 -% rn  calcium gluconate is injected in the following doses: up to 6 months - 0,1-1 ml,  7 - 12 months - 1 - 1 , 5 ml, in 1 - 3 years - 1,5 - representative sample ml, 4  - 6 years - 2 - 2,5 ml in 7 - 14 years - 3 - 5 ml; internally designate before  taking meals, adults - Table 6.2. Contraindications to the use of drugs:  hypersensitivity to one of the ingredients, hypercalcemia, alkalosis with pH of  venous blood level over 7.44 (lactate representative sample c-m c-m Burnett),  children under 6 years old weighing 20 kg. 
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