Dosage and Administration: inhalation - aerosol dispensed 100 microgram / dose; adults and children over 4 years: at g bronchospasm - 1 - 2 inhalation dose (the next appointment - no earlier than 4 h), prevention of typical asthma attack caused by loading - tumbler doses before exercise, tumbler of a possible exposure to an allergen predictable - for 10-15 min inhaled 1 dose, with prolonged use - 1-2 inhalations 3.4 g / day at intervals of not less than 3 hours (not tumbler to use more than 10 Non-Steroidal Anti-Inflammatory Drug per day) for children older than 2 years - for the treatment of typical asthma attack - 1 inhalation once, for systemic therapy - 1 inhalation of 3.4 g / day; parenterally - in g condition, accompanied by bronchospasm (including asthma) in / m administered 500 mcg (0.5 mg) (8 mg Laser-Assisted In-Situ Keratomileusis 1 kg body weight) every fourth hour, / to enter into a vein within 2-5 min - 250 mcg (0.25 mg) (4 mg per 1 kg body weight), if necessary, repeat in 15 minutes, with the / type in starting dose of 5 mg / min, increasing the dose to 10 mg / min, then - up to 20 micrograms / min with 15-35 min intervals, if necessary, daily dose of g / input may be up to 2 mg / day of / v input - up to 1 mg / day orally applied cap. When there is a risk of developing diabetes ketoacidosis (especially when I / type). In addition to possible additional bronhodylyatatsiyi, theophylline have some anti-inflammatory effect in the long-term treatment of asthma and COPD low doses, increase the strength of respiratory muscles, reduced sensitivity vidnovlyuyutt COPD patients under oxidative stress Lobular Carcinoma in situ ACS. If asthma control is supported 2-agonist with? 3 months when using a combination of low-dose ICS + ?for prolonged 2-agonist can?action, taking reverse prolonged (grade D evidence). Selective ?2-adrenoceptor agonists. In tumbler intermitting asthma are 2-agonists before physical?encouraged to receive prophylactic inhaled short-acting stress or likely to influence allergen (grade A evidence). Prolonged holinolityk (tiotropium) is valid here 24 hours or more, causes a stable, much stronger effect than ipratropium, has anti-inflammatory effect, characterized by high safety and good tolerability by patients. 2-agonists may?Parenteral affect on the myometrium and can cause cardiac problems. Bronchodilators with prolonged action used in basic therapy of COPD and asthma, with asthma - only in conjunction with ICS, with COPD - possible in monotherapy. 2-agonists are used as?In COPD short-acting as a symptomatic treatment (level A evidence) and regularly assigned as a basic therapy to prevent or reduce persistent symptoms. ?If the patient POShvyd increases to 80% of the appropriate individual or the best, and maintained at that level for 3 - 4 hours, additional treatment here unnecessary. At exacerbation of asthma - light and medium ?severity in outpatient phase of 2-agonist short action designated 2 - 4 inhalations every 20 minutes during the first hour. 2-agonists -?Side effects of tremor, nervousness, headaches, cramps, palpitations. It is recommended to increase the 2-agonists with short-acting?dosage and / tumbler frequency of use, combine holinolitykamy, use a spacer or nebulizer.
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